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Dichotomy between the transcriptomic landscape of naturally versus accelerated aged murine hearts

We investigated the transcriptomic landscape of the murine myocardium along the course of natural aging and in three distinct mouse models of premature aging with established aging-related cardiac dysfunction. Genome-wide total RNA-seq was performed and the expression patterns of protein-coding gene...

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Detalles Bibliográficos
Autores principales: De Majo, Federica, Hegenbarth, Jana-Charlotte, Rühle, Frank, Bär, Christian, Thum, Thomas, de Boer, Martine, Duncker, Dirk J., Schroen, Blanche, Armand, Anne-Sophie, Stoll, Monika, De Windt, Leon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235007/
https://www.ncbi.nlm.nih.gov/pubmed/32424227
http://dx.doi.org/10.1038/s41598-020-65115-9