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Dose-dependent skeletal deficits due to varied reductions in mechanical loading in rats

Reduced skeletal loading leads to marked bone loss. Animal models of hindlimb suspension are widely used to assess alterations in skeleton during the course of complete unloading. More recently, the effects of partial unloading on the musculoskeletal system have been interrogated in mice and rats, r...

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Detalles Bibliográficos
Autores principales: Ko, Frank C., Mortreux, Marie, Riveros, Daniela, Nagy, Janice A., Rutkove, Seward B., Bouxsein, Mary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235020/
https://www.ncbi.nlm.nih.gov/pubmed/32435691
http://dx.doi.org/10.1038/s41526-020-0105-0