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Dose-dependent skeletal deficits due to varied reductions in mechanical loading in rats
Reduced skeletal loading leads to marked bone loss. Animal models of hindlimb suspension are widely used to assess alterations in skeleton during the course of complete unloading. More recently, the effects of partial unloading on the musculoskeletal system have been interrogated in mice and rats, r...
Autores principales: | Ko, Frank C., Mortreux, Marie, Riveros, Daniela, Nagy, Janice A., Rutkove, Seward B., Bouxsein, Mary L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235020/ https://www.ncbi.nlm.nih.gov/pubmed/32435691 http://dx.doi.org/10.1038/s41526-020-0105-0 |
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