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New GMP manufacturing processes to obtain thermostable HIV-1 gp41 virosomes under solid forms for various mucosal vaccination routes

The main objective of the MACIVIVA European consortium was to develop new Good Manufacturing Practice pilot lines for manufacturing thermostable vaccines with stabilized antigens on influenza virosomes as enveloped virus-like particles. The HIV-1 gp41-derived antigens anchored in the virosome membra...

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Detalles Bibliográficos
Autores principales: Amacker, Mario, Smardon, Charli, Mason, Laura, Sorrell, Jack, Jeffery, Kirk, Adler, Michael, Bhoelan, Farien, Belova, Olga, Spengler, Mark, Punnamoottil, Beena, Schwaller, Markus, Bonduelle, Olivia, Combadière, Behazine, Stegmann, Toon, Naylor, Andrew, Johnson, Richard, Wong, Desmond, Fleury, Sylvain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235025/
https://www.ncbi.nlm.nih.gov/pubmed/32435515
http://dx.doi.org/10.1038/s41541-020-0190-9