Selected arylsulphonyl pyrazole derivatives as potential Chk1 kinase ligands—computational investigations

Protein kinases control diversity of biochemical processes in human organism. Checkpoint 1 kinase (Chk1) is an important element of the checkpoint signalling pathways and is responsible for DNA damage repair. Hence, this kinase plays an essential role in cancer cells survival and has become an impor...

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Detalles Bibliográficos
Autores principales: Czaja, Kornelia, Kujawski, Jacek, Kamel, Karol, Bernard, Marek K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235069/
https://www.ncbi.nlm.nih.gov/pubmed/32424505
http://dx.doi.org/10.1007/s00894-020-04407-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235069/
https://www.ncbi.nlm.nih.gov/pubmed/32424505
http://dx.doi.org/10.1007/s00894-020-04407-3

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