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Selected arylsulphonyl pyrazole derivatives as potential Chk1 kinase ligands—computational investigations
Protein kinases control diversity of biochemical processes in human organism. Checkpoint 1 kinase (Chk1) is an important element of the checkpoint signalling pathways and is responsible for DNA damage repair. Hence, this kinase plays an essential role in cancer cells survival and has become an impor...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235069/ https://www.ncbi.nlm.nih.gov/pubmed/32424505 http://dx.doi.org/10.1007/s00894-020-04407-3 |