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Sphingolipids produced by gut bacteria enter host metabolic pathways impacting ceramide levels

Gut microbes are linked to host metabolism, but specific mechanisms remain to be uncovered. Ceramides, a type of sphingolipid (SL), have been implicated in the development of a range of metabolic disorders from insulin resistance (IR) to hepatic steatosis. SLs are obtained from the diet and generate...

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Detalles Bibliográficos
Autores principales: Johnson, Elizabeth L., Heaver, Stacey L., Waters, Jillian L., Kim, Benjamin I., Bretin, Alexis, Goodman, Andrew L., Gewirtz, Andrew T., Worgall, Tilla S., Ley, Ruth E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235224/
https://www.ncbi.nlm.nih.gov/pubmed/32424203
http://dx.doi.org/10.1038/s41467-020-16274-w