Fibrillar form of α-synuclein-specific scFv antibody inhibits α-synuclein seeds induced aggregation and toxicity

Synucleinopathies including Parkinson’s disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA) are characterized by pathological accumulation of α-synuclein (α-syn). Amongst the various approaches attempting to tackle the pathological features of synucleinopathies, antibody...

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Detalles Bibliográficos
Autores principales: Gupta, Vijay, Salim, Safa, Hmila, Issam, Vaikath, Nishant N., Sudhakaran, Indulekha P., Ghanem, Simona S., Majbour, Nour K., Abdulla, Sara A., Emara, Mohamed M., Abdesselem, Houari B., Lukacsovich, Tamas, Erskine, Daniel, El-Agnaf, Omar M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235225/
https://www.ncbi.nlm.nih.gov/pubmed/32424162
http://dx.doi.org/10.1038/s41598-020-65035-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235225/
https://www.ncbi.nlm.nih.gov/pubmed/32424162
http://dx.doi.org/10.1038/s41598-020-65035-8

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