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Identifying inhibitors of epithelial–mesenchymal plasticity using a network topology-based approach
Metastasis is the cause of over 90% of cancer-related deaths. Cancer cells undergoing metastasis can switch dynamically between different phenotypes, enabling them to adapt to harsh challenges, such as overcoming anoikis and evading immune response. This ability, known as phenotypic plasticity, is c...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235229/ https://www.ncbi.nlm.nih.gov/pubmed/32424264 http://dx.doi.org/10.1038/s41540-020-0132-1 |