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BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells

The differentiation of human pluripotent stem cells into pancreatic cells involves cellular proliferation and apoptosis during cell fate transitions. However, their implications for establishing cellular identity are unclear. Here, we profiled the expression of BCL-2 family of proteins during pancre...

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Detalles Bibliográficos
Autores principales: Loo, Larry Sai Weng, Soetedjo, Andreas Alvin Purnomo, Lau, Hwee Hui, Ng, Natasha Hui Jin, Ghosh, Soumita, Nguyen, Linh, Krishnan, Vidhya Gomathi, Choi, Hyungwon, Roca, Xavier, Hoon, Shawn, Teo, Adrian Kee Keong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235254/
https://www.ncbi.nlm.nih.gov/pubmed/32424151
http://dx.doi.org/10.1038/s41419-020-2589-7