Interfering with retrotransposition by two types of CRISPR effectors: Cas12a and Cas13a

CRISPRs are a promising tool being explored in combating exogenous retroviral pathogens and in disabling endogenous retroviruses for organ transplantation. The Cas12a and Cas13a systems offer novel mechanisms of CRISPR actions that have not been evaluated for retrovirus interference. Particularly, a...

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Detalles Bibliográficos
Autores principales: Zhang, Niubing, Jing, Xinyun, Liu, Yuanhua, Chen, Minjie, Zhu, Xianfeng, Jiang, Jing, Wang, Hongbing, Li, Xuan, Hao, Pei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235257/
https://www.ncbi.nlm.nih.gov/pubmed/32435507
http://dx.doi.org/10.1038/s41421-020-0164-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235257/
https://www.ncbi.nlm.nih.gov/pubmed/32435507
http://dx.doi.org/10.1038/s41421-020-0164-0

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