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To Inhibit or Enhance? Is There a Benefit to Positive Allosteric Modulation of P2X Receptors?
The family of ligand-gated ion channels known as P2X receptors were discovered several decades ago. Since the cloning of the seven P2X receptors (P2X1-P2X7), a huge research effort has elucidated their roles in regulating a range of physiological and pathophysiological processes. Transgenic animals...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235284/ https://www.ncbi.nlm.nih.gov/pubmed/32477120 http://dx.doi.org/10.3389/fphar.2020.00627 |