Cargando…

To Inhibit or Enhance? Is There a Benefit to Positive Allosteric Modulation of P2X Receptors?

The family of ligand-gated ion channels known as P2X receptors were discovered several decades ago. Since the cloning of the seven P2X receptors (P2X1-P2X7), a huge research effort has elucidated their roles in regulating a range of physiological and pathophysiological processes. Transgenic animals...

Descripción completa

Detalles Bibliográficos
Autores principales: Stokes, Leanne, Bidula, Stefan, Bibič, Lučka, Allum, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235284/
https://www.ncbi.nlm.nih.gov/pubmed/32477120
http://dx.doi.org/10.3389/fphar.2020.00627