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Sphetcher: Spherical Thresholding Improves Sketching of Single-Cell Transcriptomic Heterogeneity

The massive size of single-cell RNA sequencing datasets often exceeds the capability of current computational analysis methods to solve routine tasks such as detection of cell types. Recently, geometric sketching was introduced as an alternative to uniform subsampling. It selects a subset of cells (...

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Detalles Bibliográficos
Autores principales: Do, Van Hoan, Elbassioni, Khaled, Canzar, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235285/
https://www.ncbi.nlm.nih.gov/pubmed/32438285
http://dx.doi.org/10.1016/j.isci.2020.101126