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α-Synuclein Negatively Regulates Nurr1 Expression Through NF-κB-Related Mechanism
The nuclear receptor-related 1 protein (Nurr1) is critical for the development and survival of midbrain dopamine neurons that are predominantly affected and progressively degenerated in Parkinson’s disease (PD). The expression level of Nurr1 has been proposed to be modulated by α-synuclein (α-SYN),...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235291/ https://www.ncbi.nlm.nih.gov/pubmed/32477062 http://dx.doi.org/10.3389/fnmol.2020.00064 |