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Cytoplasmic TDP43 Binds microRNAs: New Disease Targets in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive, fatal, and incurable neurodegenerative disease. Recent studies suggest that dysregulation of gene expression by microRNAs (miRNAs) may play an important role in ALS pathogenesis. The reversible nature of this dysregulation makes miRNAs attractive...

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Detalles Bibliográficos
Autores principales: Paez-Colasante, Ximena, Figueroa-Romero, Claudia, Rumora, Amy E., Hur, Junguk, Mendelson, Faye E., Hayes, John M., Backus, Carey, Taubman, Ghislaine F., Heinicke, Laurie, Walter, Nils G., Barmada, Sami J., Sakowski, Stacey A., Feldman, Eva L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235295/
https://www.ncbi.nlm.nih.gov/pubmed/32477070
http://dx.doi.org/10.3389/fncel.2020.00117