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Cytoplasmic TDP43 Binds microRNAs: New Disease Targets in Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS) is a progressive, fatal, and incurable neurodegenerative disease. Recent studies suggest that dysregulation of gene expression by microRNAs (miRNAs) may play an important role in ALS pathogenesis. The reversible nature of this dysregulation makes miRNAs attractive...
Autores principales: | Paez-Colasante, Ximena, Figueroa-Romero, Claudia, Rumora, Amy E., Hur, Junguk, Mendelson, Faye E., Hayes, John M., Backus, Carey, Taubman, Ghislaine F., Heinicke, Laurie, Walter, Nils G., Barmada, Sami J., Sakowski, Stacey A., Feldman, Eva L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235295/ https://www.ncbi.nlm.nih.gov/pubmed/32477070 http://dx.doi.org/10.3389/fncel.2020.00117 |
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