Impaired Phasic Discharge of Locus Coeruleus Neurons Based on Persistent High Tonic Discharge—A New Hypothesis With Potential Implications for Neurodegenerative Diseases

The locus coeruleus (LC) is a small brainstem nucleus with widely distributed noradrenergic projections to the whole brain, and loss of LC neurons is a prominent feature of age-related neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease (PD). This article d...

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Detalles Bibliográficos
Autor principal: Janitzky, Kathrin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235306/
https://www.ncbi.nlm.nih.gov/pubmed/32477246
http://dx.doi.org/10.3389/fneur.2020.00371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235306/
https://www.ncbi.nlm.nih.gov/pubmed/32477246
http://dx.doi.org/10.3389/fneur.2020.00371

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