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The Advent of CAR T-Cell Therapy for Lymphoproliferative Neoplasms: Integrating Research Into Clinical Practice

Research on CAR T cells has achieved enormous progress in recent years. After the impressive results obtained in relapsed and refractory B-cell acute lymphoblastic leukemia and aggressive B-cell lymphomas, two constructs, tisagenlecleucel and axicabtagene ciloleucel, were approved by FDA. The role o...

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Detalles Bibliográficos
Autores principales: Cerrano, Marco, Ruella, Marco, Perales, Miguel-Angel, Vitale, Candida, Faraci, Danilo Giuseppe, Giaccone, Luisa, Coscia, Marta, Maloy, Molly, Sanchez-Escamilla, Miriam, Elsabah, Hesham, Fadul, Afraa, Maffini, Enrico, Pittari, Gianfranco, Bruno, Benedetto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235422/
https://www.ncbi.nlm.nih.gov/pubmed/32477359
http://dx.doi.org/10.3389/fimmu.2020.00888