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Generation and validation of a highly sensitive bioluminescent HIV-1 reporter vector that simplifies measurement of virus release
BACKGROUND: The continued persistence of HIV-1 as a public health concern due to the lack of a cure calls for the development of new tools for studying replication of the virus. Here, we used NanoLuc, a small and extremely bright luciferase protein, to develop an HIV-1 bioluminescent reporter virus...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235552/ https://www.ncbi.nlm.nih.gov/pubmed/32430080 http://dx.doi.org/10.1186/s12977-020-00521-5 |