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RORγt-driven T(H)17 Cell Differentiation Requires Epigenetic Control by the Swi/Snf Chromatin Remodeling Complex
Epigenetic regulation, including chromatin accessibility and posttranslational modifications of histones, is of importance for T cell lineage decision. T(H)17 cells play a critical role in protective mucosal immunity and pathogenic multiple autoimmune diseases. The differentiation of T(H)17 cells is...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235640/ https://www.ncbi.nlm.nih.gov/pubmed/32434140 http://dx.doi.org/10.1016/j.isci.2020.101106 |