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RORγt-driven T(H)17 Cell Differentiation Requires Epigenetic Control by the Swi/Snf Chromatin Remodeling Complex

Epigenetic regulation, including chromatin accessibility and posttranslational modifications of histones, is of importance for T cell lineage decision. T(H)17 cells play a critical role in protective mucosal immunity and pathogenic multiple autoimmune diseases. The differentiation of T(H)17 cells is...

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Detalles Bibliográficos
Autores principales: Lee, Sungkyu, Kim, Jieun, Min, Hyungyu, Seong, Rho H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235640/
https://www.ncbi.nlm.nih.gov/pubmed/32434140
http://dx.doi.org/10.1016/j.isci.2020.101106