Cargando…

A molecular approach to treating cognition in schizophrenia by calcium channel blockade: An open-label pilot study of the calcium-channel antagonist isradipine

Cognitive impairment is a prominent and difficult to treat symptom in schizophrenia (SZ), which is directly related to functional disability. A variant in the gene coding for the alpha 1C subunit of L-type voltage gated calcium channel (CACNA1C) has been shown to negatively affect several neurocogni...

Descripción completa

Detalles Bibliográficos
Autores principales: Burdick, Katherine E., Perez-Rodriguez, Mercedes, Birnbaum, Rebecca, Shanahan, Megan, Larsen, Emmett, Harper, Cierra, Poskus, Jessica, Sklar, Pamela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235642/
https://www.ncbi.nlm.nih.gov/pubmed/32455122
http://dx.doi.org/10.1016/j.scog.2020.100180