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A molecular approach to treating cognition in schizophrenia by calcium channel blockade: An open-label pilot study of the calcium-channel antagonist isradipine
Cognitive impairment is a prominent and difficult to treat symptom in schizophrenia (SZ), which is directly related to functional disability. A variant in the gene coding for the alpha 1C subunit of L-type voltage gated calcium channel (CACNA1C) has been shown to negatively affect several neurocogni...
Autores principales: | Burdick, Katherine E., Perez-Rodriguez, Mercedes, Birnbaum, Rebecca, Shanahan, Megan, Larsen, Emmett, Harper, Cierra, Poskus, Jessica, Sklar, Pamela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235642/ https://www.ncbi.nlm.nih.gov/pubmed/32455122 http://dx.doi.org/10.1016/j.scog.2020.100180 |
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