Cargando…

Sustained adenosine exposure causes endothelial mitochondrial dysfunction via equilibrative nucleoside transporters

Adenosine is a potent signaling molecule that has paradoxical effects on lung diseases. We have previously demonstrated that sustained adenosine exposure by inhibition of adenosine degradation impairs lung endothelial barrier integrity and causes intrinsic apoptosis through equilibrative nucleoside...

Descripción completa

Detalles Bibliográficos
Autores principales: Ko, Junsuk, Rounds, Sharon, Lu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235668/
https://www.ncbi.nlm.nih.gov/pubmed/32523687
http://dx.doi.org/10.1177/2045894020924994