Cargando…

Two-Step Size-Exclusion Nanofiltration of Prothrombin Complex Concentrate Using Nanocellulose-Based Filter Paper

Coagulation Factor IX-rich protrhombin complex concentrate (FIX-PCC) is a therapeutic biologic product that consists of a mixture of several human plasma-derived proteins, useful for treating hemophilia B. Due to its complex composition, FIX-PCC is very challenging to bioprocess through virus removi...

Descripción completa

Detalles Bibliográficos
Autores principales: Manukyan, Levon, Mantas, Athanasios, Razumikhin, Mikhail, Katalevsky, Andrey, Golubev, Eugen, Mihranyan, Albert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235758/
https://www.ncbi.nlm.nih.gov/pubmed/32224972
http://dx.doi.org/10.3390/biomedicines8040069