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Two-Step Size-Exclusion Nanofiltration of Prothrombin Complex Concentrate Using Nanocellulose-Based Filter Paper
Coagulation Factor IX-rich protrhombin complex concentrate (FIX-PCC) is a therapeutic biologic product that consists of a mixture of several human plasma-derived proteins, useful for treating hemophilia B. Due to its complex composition, FIX-PCC is very challenging to bioprocess through virus removi...
Autores principales: | Manukyan, Levon, Mantas, Athanasios, Razumikhin, Mikhail, Katalevsky, Andrey, Golubev, Eugen, Mihranyan, Albert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235758/ https://www.ncbi.nlm.nih.gov/pubmed/32224972 http://dx.doi.org/10.3390/biomedicines8040069 |
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