Piperine Inhibits TGF-β Signaling Pathways and Disrupts EMT-Related Events in Human Lung Adenocarcinoma Cells

Background: Piperine, an amide extracted from the Piper spices, exhibits strong anti-tumor properties. However, its effect on the epithelial–mesenchymal transition (EMT) process has never been investigated. Herein, we evaluate the toxic effect of piperine on lung adenocarcinoma (A549), breast adenoc...

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Detalles Bibliográficos
Autores principales: Marques da Fonseca, Leonardo, Jacques da Silva, Lucas Rodrigues, Santos dos Reis, Jhenifer, Rodrigues da Costa Santos, Marcos André, de Sousa Chaves, Victoria, Monteiro da Costa, Kelli, Sa-Diniz, Julliana de Nazareth, Freire de Lima, Celio Geraldo, Morrot, Alexandre, Nunes Franklim, Tatiany, de Alcântara-Pinto, Douglas Chaves, Freire de Lima, Marco Edilson, Previato, Jose Osvaldo, Mendonça-Previato, Lucia, Freire-de-Lima, Leonardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235759/
https://www.ncbi.nlm.nih.gov/pubmed/32276474
http://dx.doi.org/10.3390/medicines7040019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235759/
https://www.ncbi.nlm.nih.gov/pubmed/32276474
http://dx.doi.org/10.3390/medicines7040019

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