PBMC of Multiple Sclerosis Patients Show Deregulation of OPA1 Processing Associated with Increased ROS and PHB2 Protein Levels

Multiple sclerosis (MS) is an autoimmune disease in which activated lymphocytes affect the central nervous system. Increase of reactive oxygen species (ROS), impairment of mitochondria-mediated apoptosis and mitochondrial alterations have been reported in peripheral lymphocytes of MS patients. Mitoc...

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Detalles Bibliográficos
Autores principales: De Rasmo, Domenico, Ferretta, Anna, Russo, Silvia, Ruggieri, Maddalena, Lasorella, Piergiorgio, Paolicelli, Damiano, Trojano, Maria, Signorile, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235786/
https://www.ncbi.nlm.nih.gov/pubmed/32290388
http://dx.doi.org/10.3390/biomedicines8040085

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235786/
https://www.ncbi.nlm.nih.gov/pubmed/32290388
http://dx.doi.org/10.3390/biomedicines8040085

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