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Intratumoral Genomic Heterogeneity May Hinder Precision Medicine Strategies in Patients with Serous Ovarian Carcinoma

Precision medicine, which includes comprehensive genome sequencing, is a potential therapeutic option for treating high-grade serous carcinoma (HGSC). However, HGSC is a heterogeneous tumor at the architectural, cellular, and molecular levels. Intratumoral molecular heterogeneity currently limits th...

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Detalles Bibliográficos
Autores principales: Nakamura, Kohei, Aimono, Eriko, Tanishima, Shigeki, Imai, Mitsuho, Nagatsuma, Akiko Kawano, Hayashi, Hideyuki, Yoshimura, Yuki, Nakayama, Kentaro, Kyo, Satoru, Nishihara, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235797/
https://www.ncbi.nlm.nih.gov/pubmed/32260152
http://dx.doi.org/10.3390/diagnostics10040200