Pharmacokinetics of Macrolide Antibiotics and Transport into the Interstitial Fluid: Comparison among Erythromycin, Clarithromycin, and Azithromycin

Recent research has found higher levels and longer total exposure of azithromycin, a macrolide antibiotic agent, in the interstitial fluid of the skin than in the plasma. This unique distribution is expected to contribute to its antimicrobial activity at the primary infection site. However, it remai...

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Detalles Bibliográficos
Autores principales: Kobuchi, Shinji, Kabata, Teruhiko, Maeda, Koki, Ito, Yukako, Sakaeda, Toshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235806/
https://www.ncbi.nlm.nih.gov/pubmed/32331283
http://dx.doi.org/10.3390/antibiotics9040199

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235806/
https://www.ncbi.nlm.nih.gov/pubmed/32331283
http://dx.doi.org/10.3390/antibiotics9040199

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