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Benzamide Derivatives Targeting the Cell Division Protein FtsZ: Modifications of the Linker and the Benzodioxane Scaffold and Their Effects on Antimicrobial Activity

Filamentous temperature-sensitive Z (FtsZ) is a prokaryotic protein with an essential role in the bacterial cell division process. It is widely conserved and expressed in both Gram-positive and Gram-negative strains. In the last decade, several research groups have pointed out molecules able to targ...

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Detalles Bibliográficos
Autores principales: Straniero, Valentina, Suigo, Lorenzo, Casiraghi, Andrea, Sebastián-Pérez, Victor, Hrast, Martina, Zanotto, Carlo, Zdovc, Irena, De Giuli Morghen, Carlo, Radaelli, Antonia, Valoti, Ermanno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235863/
https://www.ncbi.nlm.nih.gov/pubmed/32260339
http://dx.doi.org/10.3390/antibiotics9040160