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Actinobacterial Coproheme Decarboxylases Use Histidine as a Distal Base to Promote Compound I Formation

[Image: see text] Coproheme decarboxylases (ChdCs) catalyze the final step in heme b biosynthesis of monoderm and some diderm bacteria. In this reaction, coproheme is converted to heme b via monovinyl monopropionate deuteroheme (MMD) in two consecutive decarboxylation steps. In Firmicutes decarboxyl...

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Detalles Bibliográficos
Autores principales: Michlits, Hanna, Lier, Bettina, Pfanzagl, Vera, Djinović-Carugo, Kristina, Furtmüller, Paul G., Oostenbrink, Chris, Obinger, Christian, Hofbauer, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7235987/
https://www.ncbi.nlm.nih.gov/pubmed/32440366
http://dx.doi.org/10.1021/acscatal.0c00411