Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism

Maintaining a balance between protein degradation and protein synthesis is necessary for neurodevelopment. Although the E3 ubiquitin ligase anaphase promoting complex and its regulatory subunit Cdh1 (Cdh1-APC) has been shown to regulate learning and memory, the underlying mechanisms are unclear. Her...

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Detalles Bibliográficos
Autores principales: Valdez-Sinon, Arielle N., Lai, Austin, Shi, Liang, Lancaster, Carly L., Gokhale, Avanti, Faundez, Victor, Bassell, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236060/
https://www.ncbi.nlm.nih.gov/pubmed/32434143
http://dx.doi.org/10.1016/j.isci.2020.101132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236060/
https://www.ncbi.nlm.nih.gov/pubmed/32434143
http://dx.doi.org/10.1016/j.isci.2020.101132

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