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Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism
Maintaining a balance between protein degradation and protein synthesis is necessary for neurodevelopment. Although the E3 ubiquitin ligase anaphase promoting complex and its regulatory subunit Cdh1 (Cdh1-APC) has been shown to regulate learning and memory, the underlying mechanisms are unclear. Her...
Autores principales: | Valdez-Sinon, Arielle N., Lai, Austin, Shi, Liang, Lancaster, Carly L., Gokhale, Avanti, Faundez, Victor, Bassell, Gary J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236060/ https://www.ncbi.nlm.nih.gov/pubmed/32434143 http://dx.doi.org/10.1016/j.isci.2020.101132 |
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