Circular RNA circMET drives immunosuppression and anti-PD1 therapy resistance in hepatocellular carcinoma via the miR-30-5p/snail/DPP4 axis

BACKGROUND: Amplification of chromosome 7q21-7q31 is associated with tumor recurrence and multidrug resistance, and several genes in this region are powerful drivers of hepatocellular carcinoma (HCC). We aimed to investigate the key circular RNAs (circRNAs) in this region that regulate the initiatio...

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Detalles Bibliográficos
Autores principales: Huang, Xiao-Yong, Zhang, Peng-Fei, Wei, Chuan-Yuan, Peng, Rui, Lu, Jia-Cheng, Gao, Chao, Cai, Jia-Bing, Yang, Xuan, Fan, Jia, Ke, Ai-Wu, Zhou, Jian, Shi, Guo-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236145/
https://www.ncbi.nlm.nih.gov/pubmed/32430013
http://dx.doi.org/10.1186/s12943-020-01213-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236145/
https://www.ncbi.nlm.nih.gov/pubmed/32430013
http://dx.doi.org/10.1186/s12943-020-01213-6

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