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Inhibition of HMGB1 Overcomes Resistance to Radiation and Chemotherapy in Nasopharyngeal Carcinoma

OBJECTIVE: This study aimed to investigate the effect of high mobility group protein B1 (HMGB1) on chemoresistance and radioresistance in nasopharyngeal carcinoma (NPC). MATERIALS AND METHODS: HMGB1-knockout HK1 cell lines were generated using clustered regularly interspaced short palindromic repeat...

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Detalles Bibliográficos
Autores principales: Zhu, Xuewei, Cong, Jianan, Lin, Zhang, Sun, Jing, Yang, Ben, Li, Aipeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236242/
https://www.ncbi.nlm.nih.gov/pubmed/32523355
http://dx.doi.org/10.2147/OTT.S239243