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MiR-223 plays a protecting role in neutrophilic asthmatic mice through the inhibition of NLRP3 inflammasome

BACKGROUND: Neutrophilic subtype asthma occurs in approximately 15–25% of the asthma cases and is associated with severe airflow obstruction, corticosteroid resistance. MicroRNA plays a vital role in regulating many immune processes, but how miRNA circuits coordinate airway inflammation during neutr...

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Detalles Bibliográficos
Autores principales: Xu, Wenjuan, Wang, Yimin, Ma, Ying, Yang, Jiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236263/
https://www.ncbi.nlm.nih.gov/pubmed/32423405
http://dx.doi.org/10.1186/s12931-020-01374-4