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Loss of homeostatic microglial phenotype in CSF1R-related Leukoencephalopathy
Microglia are resident macrophages of the central nervous system, and their unique molecular signature is dependent upon CSF-1 signaling. Previous studies have demonstrated the importance of CSF-1R in survival and development of microglia in animal models, but the findings are of uncertain relevance...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236286/ https://www.ncbi.nlm.nih.gov/pubmed/32430064 http://dx.doi.org/10.1186/s40478-020-00947-0 |