In Silico Study of Correlation between Missense Variations of F8 Gene and Inhibitor Formation in Severe Hemophilia A

OBJECTIVE: Deleterious substitutions of the F8 gene are responsible for causing hemophilia A, which is an inherited bleeding disorder resulting from reduced or absent activity of the coagulant protein factor VIII (FVIII). The most important complication in treatment is inhibitor development toward t...

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Detalles Bibliográficos
Autores principales: Fodil, Mostefa, Zemani, Faouzia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236410/
https://www.ncbi.nlm.nih.gov/pubmed/31876401
http://dx.doi.org/10.4274/tjh.galenos.2019.2019.0094

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236410/
https://www.ncbi.nlm.nih.gov/pubmed/31876401
http://dx.doi.org/10.4274/tjh.galenos.2019.2019.0094

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