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PTEN and AKT1 Variations in Childhood T-Cell Acute Lymphoblastic Leukemia

OBJECTIVE: PTEN/AKT pathway deregulations have been reported to be associated with treatment response in acute leukemia. This study examined pediatric T-cell acute lymphoblastic leukemia (T-ALL) samples for PTEN and AKT1 gene variations and evaluated the clinical findings. MATERIALS AND METHODS: Fif...

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Detalles Bibliográficos
Autores principales: Küçükcankurt, Fulya, Erbilgin, Yücel, Fırtına, Sinem, Hatırnaz Ng, Özden, Karakaş, Zeynep, Celkan, Tiraje, Ünüvar, Ayşegül, Özbek, Uğur, Sayitoğlu, Müge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236415/
https://www.ncbi.nlm.nih.gov/pubmed/31744268
http://dx.doi.org/10.4274/tjh.galenos.2019.2019.0282