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Putative functional non-coding polymorphisms in SELP significantly modulate sP-selectin levels, arterial stiffness and type 2 diabetes mellitus susceptibility

BACKGROUND: P-selectin, encoded by SELP, has been implicated as an important molecule in the development of arterial stiffness, consequently leading to vascular complications in T2DM. SELP polymorphisms and increased levels of soluble P-selectin (sP-selectin) have been shown to be associated with se...

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Detalles Bibliográficos
Autores principales: Kaur, Raminderjit, Singh, Jatinder, Kapoor, Rohit, Kaur, Manpreet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236446/
https://www.ncbi.nlm.nih.gov/pubmed/32429899
http://dx.doi.org/10.1186/s12902-020-00548-x