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Mitochondrial tRNA methylation in Alzheimer’s disease and progressive supranuclear palsy
BACKGROUND: Methylation of mitochondrial tRNAs (mt-tRNA) at the 9th position (“p9 site”) is known to impact translational efficiency and downstream mitochondrial function; however, direct assessment of mt-RNA methylation is challenging. Recent RNA sequence-based methods have been developed to reliab...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236490/ https://www.ncbi.nlm.nih.gov/pubmed/32429992 http://dx.doi.org/10.1186/s12920-020-0727-9 |