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BpForms and BcForms: a toolkit for concretely describing non-canonical polymers and complexes to facilitate global biochemical networks

Non-canonical residues, caps, crosslinks, and nicks are important to many functions of DNAs, RNAs, proteins, and complexes. However, we do not fully understand how networks of such non-canonical macromolecules generate behavior. One barrier is our limited formats for describing macromolecules. To ov...

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Detalles Bibliográficos
Autores principales: Lang, Paul F., Chebaro, Yassmine, Zheng, Xiaoyue, P. Sekar, John A., Shaikh, Bilal, Natale, Darren A., Karr, Jonathan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236495/
https://www.ncbi.nlm.nih.gov/pubmed/32423472
http://dx.doi.org/10.1186/s13059-020-02025-z