Protection from DNA re-methylation by transcription factors in primordial germ cells and pre-implantation embryos can explain trans-generational epigenetic inheritance

BACKGROUND: A growing body of evidence suggests that certain epiphenotypes can be passed across generations via both the male and female germlines of mammals. These observations have been difficult to explain owing to a global loss of the majority of known epigenetic marks present in parental chromo...

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Detalles Bibliográficos
Autores principales: Kremsky, Isaac, Corces, Victor G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236515/
https://www.ncbi.nlm.nih.gov/pubmed/32423419
http://dx.doi.org/10.1186/s13059-020-02036-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236515/
https://www.ncbi.nlm.nih.gov/pubmed/32423419
http://dx.doi.org/10.1186/s13059-020-02036-w

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