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The proteasome as a druggable target with multiple therapeutic potentialities: Cutting and non-cutting edges
Ubiquitin Proteasome System (UPS) is an adaptable and finely tuned system that sustains proteostasis network under a large variety of physiopathological conditions. Its dysregulation is often associated with the onset and progression of human diseases; hence, UPS modulation has emerged as a promisin...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236745/ https://www.ncbi.nlm.nih.gov/pubmed/32442437 http://dx.doi.org/10.1016/j.pharmthera.2020.107579 |