Extracellular Sortilin Proteopathy Relative to β-Amyloid and Tau in Aged and Alzheimer’s Disease Human Brains

Amyloid plaques and neurofibrillary tangles (NFTs) are hallmark lesions of Alzheimer’s disease (AD) related to β-amyloid (Aβ) deposition and intraneuronal phosphorylated tau (pTau) accumulation. Sortilin C-terminal fragments (shortened as “sorfra”) can deposit as senile plaque-like lesions within AD...

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Detalles Bibliográficos
Autores principales: Tu, Tian, Jiang, Juan, Zhang, Qi-Lei, Wan, Lily, Li, Ya-Nan, Pan, Aihua, Manavis, Jim, Yan, Xiao-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236809/
https://www.ncbi.nlm.nih.gov/pubmed/32477092
http://dx.doi.org/10.3389/fnagi.2020.00093

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236809/
https://www.ncbi.nlm.nih.gov/pubmed/32477092
http://dx.doi.org/10.3389/fnagi.2020.00093

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