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Extracellular Sortilin Proteopathy Relative to β-Amyloid and Tau in Aged and Alzheimer’s Disease Human Brains

Amyloid plaques and neurofibrillary tangles (NFTs) are hallmark lesions of Alzheimer’s disease (AD) related to β-amyloid (Aβ) deposition and intraneuronal phosphorylated tau (pTau) accumulation. Sortilin C-terminal fragments (shortened as “sorfra”) can deposit as senile plaque-like lesions within AD...

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Detalles Bibliográficos
Autores principales:	Tu, Tian, Jiang, Juan, Zhang, Qi-Lei, Wan, Lily, Li, Ya-Nan, Pan, Aihua, Manavis, Jim, Yan, Xiao-Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236809/ https://www.ncbi.nlm.nih.gov/pubmed/32477092 http://dx.doi.org/10.3389/fnagi.2020.00093

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