Overexpression of MIG-6 in the cartilage induces an osteoarthritis-like phenotype in mice

BACKGROUND: Osteoarthritis (OA) is the most common form of arthritis and characterized by degeneration of the articular cartilage. Mitogen-inducible gene 6 (Mig-6) has been identified as a negative regulator of the epidermal growth factor receptor (EGFR). Cartilage-specific Mig-6 knockout (KO) mice...

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Detalles Bibliográficos
Autores principales: Bellini, Melina, Pest, Michael A., Miranda-Rodrigues, Manuela, Qin, Ling, Jeong, Jae-Wook, Beier, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236969/
https://www.ncbi.nlm.nih.gov/pubmed/32430054
http://dx.doi.org/10.1186/s13075-020-02213-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7236969/
https://www.ncbi.nlm.nih.gov/pubmed/32430054
http://dx.doi.org/10.1186/s13075-020-02213-z

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