sEH Inhibitor Tppu Ameliorates Cecal Ligation and Puncture-Induced Sepsis by Regulating Macrophage Functions

BACKGROUND: Sepsis is a life-threatening organ dysfunction initiated by a dysregulated response to infection, with imbalanced inflammation and immune homeostasis. Macrophages play a pivotal role in sepsis. N-[1-(1-oxopropyl)-4-piperidinyl]-N’-[4-(trifluoromethoxy)phenyl)-urea (TPPU) is an inhibitor...

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Detalles Bibliográficos
Autores principales: Chen, Zhihui, Tang, Ying, Yu, Jing, Dong, Ruolan, Yang, Yan, Fu, Menglu, Luo, Jinlan, Hu, Shuiqing, Wang, Dao Wen, Tu, Ling, Xu, Xizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Basic Science Aspects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237073/
https://www.ncbi.nlm.nih.gov/pubmed/31318834
http://dx.doi.org/10.1097/SHK.0000000000001408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237073/
https://www.ncbi.nlm.nih.gov/pubmed/31318834
http://dx.doi.org/10.1097/SHK.0000000000001408

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