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DNMT1 Enhances the Radiosensitivity of HPV-Positive Head and Neck Squamous Cell Carcinomas via Downregulating SMG1

INTRODUCTION: Head and neck squamous cell carcinoma (HNSCC), which rank the 7th malignant tumors worldwide, is closely related to methylation and HPV infection. Ionizing radiation therapy is the main strategy for HNSCC patients in advanced stage. Previously, HPV-positive HNSCC predict better prognos...

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Detalles Bibliográficos
Autores principales: Zhang, Chunlin, Mi, Jiaoping, Deng, Yuan, Deng, Zeyi, Long, Dan, Liu, Zhaohui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237113/
https://www.ncbi.nlm.nih.gov/pubmed/32523356
http://dx.doi.org/10.2147/OTT.S227395