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TRMT2B is responsible for both tRNA and rRNA m(5)U-methylation in human mitochondria

RNA species play host to a plethora of post-transcriptional modifications which together make up the epitranscriptome. 5-methyluridine (m(5)U) is one of the most common modifications made to cellular RNA, where it is found almost ubiquitously in bacterial and eukaryotic cytosolic tRNAs at position 5...

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Detalles Bibliográficos
Autores principales: Powell, Christopher A., Minczuk, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7237155/
https://www.ncbi.nlm.nih.gov/pubmed/31948311
http://dx.doi.org/10.1080/15476286.2020.1712544